TheBioMLClinic

TheBioMLClinic

TheBioMLClinic

AIxAAV Interpreter

AIxAAV Interpreter

AIxAAV Interpreter

AAV-ML Fluency for AAV Experimentalists & AAV Translational Ideas

AAV-ML Fluency for AAV Experimentalists & AAV Translational Ideas

AAV-ML Fluency


Where I write articles for AAV scientists about what ML can and cannot do in their programs, what to adopt, what to question, and why. An honest read of what the field is doing and where it falls short.


Where I write articles for AAV scientists about what ML can and cannot do in their programs, what to adopt, what to question, and why. An honest read of what the field is doing and where it falls short.


Why AlphaFold Won't Engineer Your Next AAV Capsid
Read →

Why Protein Language Models (PLMs) won't let you explore distant AAV capsids + how to fix it
Read →

Stop Trying to Fix Toxic AAV Variants (with or without ML)
Read →

When You Only Have 1,000 Potential Hits
Read →

Skip the Data Bottleneck: Designing Capsids for Serotypes You Have No Data On
Read →

AI Is Not Coming for AAV Scientist Jobs. We Are Worried About the Wrong Thing
 2-min Read → 5-min Read → 10-min Read →




Why AlphaFold Won't Engineer Your Next AAV Capsid
Read →

Why Protein Language Models (PLMs) won't let you explore distant AAV capsids + how to fix it
Read →

Stop Trying to Fix Toxic AAV Variants (with or without ML)
Read →

When You Only Have 1,000 Potential Hits
Read →

Skip the Data Bottleneck: Designing Capsids for Serotypes You Have No Data On
Read →

AI Is Not Coming for AAV Scientist Jobs. We Are Worried About the Wrong Thing
 2-min Read →
5-min Read →
10-min Read →




Why AlphaFold Won't Engineer Your Next AAV Capsid
Read →

Why Protein Language Models (PLMs) won't let you explore distant AAV capsids + how to fix it
Read →

Stop Trying to Fix Toxic AAV Variants (with or without ML)
Read →

When You Only Have 1,000 Potential Hits
Read →

Skip the Data Bottleneck: Designing Capsids for Serotypes You Have No Data On
Read →

AI Is Not Coming for AAV Scientist Jobs. We Are Worried About the Wrong Thing
 2-min Read →
5-min Read →
10-min Read →



AAV Translational Idea


Short articles I write on LinkedIn translating ideas from other fields that AAV is yet to borrow.



Short articles I write on LinkedIn translating ideas from other fields that AAV is yet to borrow.



The LNP Field Just Handed AAV the In Vivo Endosomal Escape Assay It Never Had
Read →

Scaling Lysosomal Fate Measurement Across Thousands of AAV Variants. And Using It to Train ML Models
Read →

What a Mucin-Binding Shuttle from the Biologic World Reveals About Untapped Entry Routes for CNS AAV
Read →

What a CAR T Manufacturing Problem Revealed About Capsid Immune Evasion. And What AAV Engineers Should Steal From It
Read →

The First Atomic-Resolution Structure of Rep Packaging AAV Gives Every Full/Empty Ratio Problem a Molecular Address
Read →





We hope this gives you a clearer starting point.

— TheBioMLClinic

We hope it gives you a clearer starting point.

— TheBioMLClinic

We hope it gives you a clearer starting point.

— TheBioMLClinic